Dr. Dean Edell: Janis Schonfeld says she suffered from depression since she was a teen, but she didn't get professional help until her early 40s.
Janis Schonfeld: I would tear and cry for no reason, just driving my daughter to school.
Dr. Dean Edell: Sallie Broadway's anxiety disorders put her on the other end of the mood spectrum.
Sallie Broadway: My eyes start, like I have an eye twitch, and I start feeling like I can't breathe and I am having a heart attack.
Dr. Dean Edell: Although Sallie's condition seems opposite of Janis', more than 60% of generalized anxiety patients also suffer from depression.
David Hellerstein: They both affect your functioning, and they are both related to abnormalities of brain chemicals.
Dr. Dean Edell: Brain chemicals called neurotransmitters.
Hyla Cass: Neurotransmitters are the feel good chemical messengers that make our brain function.
Dr. Dean Edell: Researches believe when certain transmitters, like serotonin and norepinephrine, are off-balance, it can lead to depression or anxiety.
Male Speaker: It's how the brain is processing the transmitters. It's kind of like a car that is not tuned up very well will tend to run out of gas more quickly.
Dr. Dean Edell: Traditional antidepressants work on only one transmitter, while dual reuptake inhibitors work on both. Medication didn't work for Sallie, but it did for Janis.
Janis Schonfeld: I feel fine. I actually continue to feel even better.
Dr. Dean Edell: Today, her depression is gone, and she is glad to be back to her old self. I am Dr. Dean Edell.
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