Jennifer Matthews: Frank Di Paolo junior is 100 years old.
Frank Di Paolo: I am, honestly, 100 and half years old, Di Paolo says.
Jennifer Matthews: And he doesn't miss a beat! He drives to work every day, working in the office of a state senator.
Frank Di Paolo: I honestly believe that if you get enough rest, you exercise some, you eat well, you're going to live.
Jennifer Matthews: One secret he believes to living a long life ... red wine.
Frank Di Paolo: I think this has a lot to do with getting old.
Jennifer Matthews: In fact, red wine contains polyphenols -- chemicals that some research has shown can ward-off heart disease.
Dr. Thomas Perls has studied centenarians for more than decade.
Want to know how long you'll live? Take a look at your relatives. Dr. Perls believes 30 percent of how well we'll age is in our genes.
Dr. Thomas Perls: Our studies show exceptional longevity, which means living to 100 or older, runs very strongly in families.
Jennifer Matthews: Centenarians also tend to have certain personality traits.
Dr. Thomas Perls: Many of them had very, very stressful lives, but what seems to be the key to them is they don't hold on to stuff. They don't dwell on it.
Jennifer Matthews: They are rarely depressed.
Ellen Doble: I always laugh.
Jennifer Matthews: Genetic variations also slow down the aging process. In fact, 20 percent of centenarians, like Ellen had children after the age of 40, their fertility a marker for the rest of their body.
Dr. Thomas Perls: Who would ever want to live to be 100? Dr. Perls asks.
Jennifer Matthews: Studies show centenarians have 60 percent lower rates of heart disease, stroke and high blood pressure.
Dr. Thomas Perls: One of the reasons centenarians are rare, not a rare one single factor, but rather, it's the combination of factors that makes them rare. It's a bit like winning the lottery. If you have one or two numbers, it's pretty easy, but getting seven numbers, that makes you rare.
Jennifer Matthews: That combination of luck, lifestyle and genes can add up to a very long life.
Frank Di Paolo: You know, I got it in here that I'm going to live ten more years, Di Paolo says.
Jennifer Matthews: This is Jennifer Matthews reporting.
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