Jennifer Mathews: After 50 years of marriage, photos bring back memories for Millard and Sybil Goffstein.
Millard Goffstein: We have a very happy life together.
Sybil Goffstein: He still eats what I cook.
Jennifer Mathews: But those memories are fading. Sybil has Alzheimer's disease. Her diagnosis brings back memories of living through war.
Sybil Goffstein: You hear bombs dropping all around you, and you expect to be blown out. So that's the same with this illness.
Jennifer Mathews: Her attitude soon changes.
Sybil Goffstein: I just thought what is to be afraid of. There isn't nothing to be afraid of.
Jennifer Mathews: Dr. George Grossberg hopes this new drug, NS-2330, will help those mood swings.
Dr. George T. Grossberg: It has beneficial effects on a variety of brain chemicals that are adversely affected by Alzheimer's disease.
Jennifer Mathews: All current medications work just on the brain chemical that controls memory. NS-2330 helps memory and also increases serotonin and norepinephrine. Serotonin helps mood, anxiety, and irritability. Norepinephrine helps depression, energy, and apathy.
Dr. George T. Grossberg: That gives, I think, patients and families hope for addressing more completely the various symptoms of Alzheimer's disease.
Jennifer Mathews: Sybil is aware of what the drug could be doing for her.
Sybil Goffstein: I do want my brain to stay with its grip, to be able to know where I am, how I am.
Millard Goffstein: I'm just praying that she doesn't deteriorate any further, and that, God willing, somewhere along the line, they come up with a solution.
Jennifer Mathews: Until then, they are taking life one memory at a time. This is Jennifer Mathews reporting.
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