Pharmaceuticals: Percocet
Sandra Takami, PharmD.
Nuclear Pharmacist, Memorial Sloan Kettering
Doctor of Pharmacy, USC
Percocet is the brand name for the compound that contains oxycodone or narcotic and acetaminophen which was approved by the FDA in 1999.
Oxycodone is a prescription narcotic. They can be combined with acetaminophen, the active ingredient in Tylenol to produce a potent pain killer. The compound is available as a generic drug and under brand names like Endocet and Percocet. When oxycodone enters the central nervous system, it binds the opiod receptors located in the brain and spinal cord. This relieves pain by blocking out the body’s natural response to discomfort. Although oxycodone is technically an antitussin or cough suppressant, it is prescribed almost exclusively to treat severe pain. When acetaminophen and oxycodone are combined, the compound treats pain more effectively than either medication does individually.
The oxycodone and acetaminophen compound is available in tablet, capsule or liquid form. The medication combines five to 10 mg of oxycodone with 325 mg to 500 mg of acetaminophen. Be careful to take oxycodone and acetaminophen only as directed by your doctor and never stop treatment suddenly. Take this compound with milk or with food.
The most common side effects of oxycodone with acetaminophen are constipation, nausea, vomiting, and dizziness but you should ask your doctor for a complete list. Also be sure to tell your physician immediately if you experienced slow breathing, clammy skin, weakness, extreme sleepiness, or other significant changes. Oxycodone with acetaminophen should never be taken in conjunction with Naltrexone, alcohol, antihistamines or antidepressants. Ask your doctor for a full list of medications and conditions that should not be combined with oxycodone.
Percocet can often help people cope with chronic pain. However, the drug should always be used under the direct care of a physician. Please ask for, and review all of the information provided by your doctor before taking oxycodone with acetaminophen.
The information in this video is intended to supplement not substitute for the prescribing instructions and the expertise of your physician. Always consult your doctor before using this drug.
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